Mr Griffiths has an interest in academic research and audit and the following publications have been published in peer reviewed medical journals on the following aspects:

Preoperative risk factors for conversion from laparoscopic to open cholecystectomy: a validated risk score derived from a prospective U.K. database of 8820 patients.

Sutcliffe RP, Hollyman M, Hodson J, Bonney G, Vohra RS, Griffiths EA; CholeS study group, West Midlands Research Collaborative.
HPB (Oxford). 2016 Aug 30.

Population-based cohort study of outcomes following cholecystectomy for benign gallbladder diseases.

CholeS Study Group, West Midlands Research Collaborative. Griffiths EA Corresponding Author
Br J Surg. 2016 Aug 26

Meta-analysis of perioperative antibiotics in patients undergoing laparoscopic cholecystectomy.

Pasquali S, Boal M, Griffiths EA, Alderson D, Vohra RS; CholeS Study Group and the West Midlands Research Collaborative.
Br J Surg. 2016 Jan;103(1):27-34

Protocol for a multicentre, prospective, population-based cohort study of variation in practice of cholecystectomy and surgical outcomes (The CholeS study).

Vohra RS, Spreadborough P, Johnstone M, Marriott P, Bhangu A, Alderson D, Morton DG, Griffiths EA; West Midlands Research Collaborative.
BMJ Open. 2015 Jan 12;5(1):e006399

The learning curve to achieve satisfactory completion rates in upper GI endoscopy: an analysis of a national training database.

Ward ST, Hancox A, Mohammed MA, Ismail T, Griffiths EA, Valori R, Dunckley P.
Gut. 2016 Mar 14

Survival After Neoadjuvant and Adjuvant Treatments Compared to Surgery Alone for Resectable Esophageal Carcinoma: A Network Meta-analysis.

Pasquali S, Yim G, Vohra RS, Mocellin S, Nyanhongo D, Marriott P, Geh JI, Griffiths EA.
Ann Surg. 2016 Jul 15. [Epub ahead of print]

Should routine radiological assessment of anastomotic integrity be performed after oesophagectomy with cervical anastomosis? Best evidence topic (BET).

Jones CM, Heah R, Clarke B, Griffiths EA.
Int J Surg. 2015 Feb 7

What is the best neoadjuvant regimen prior to oesophagectomy: chemotherapy or chemoradiotherapy?

Hamilton E, Vohra RS, Griffiths EA.
Int J Surg. 2014;12(3):196-9.

Re: Is an involved circumferential resection margin following oesphagectomy for cancer an important prognostic indicator?

Griffiths EA, Pritchard SA.
Interact Cardiovasc Thorac Surg. 2010 Nov;11(5):648

Tumour budding and a low host inflammatory response are associated with a poor prognosis in oesophageal and gastro-oesophageal junction cancers.

Brown M, Sillah K, Griffiths EA, Swindell R, West CM, Page RD, Welch IM, Pritchard SA.
Histopathology. 2010 Jun;56(7):893-9.

Clinical impact of tumour involvement of the anastomotic doughnut in oesophagogastric cancer surgery.

Sillah K, Griffiths EA, Pritchard SA, Swindell R, West CM, Page R, Welch IM.
Ann R Coll Surg Engl. 2009 Apr;91(3):195-200

Emerging aspects of oesophageal and gastro-oesophageal junction cancer histopathology – an update for the surgical oncologist.

Griffiths EA, Pritchard SA, Mapstone NP, Welch IM.
World J Surg Oncol. 2006 Nov 21;4:82.

The prognostic value of circumferential resection margin involvement in oesophageal malignancy.

Griffiths EA, Brummell Z, Gorthi G, Pritchard SA, Welch IM.
Eur J Surg Oncol. 2006 May;32(4):413-9

Tumor length as a prognostic factor in esophageal malignancy: univariate and multivariate survival analyses.

Griffiths EA, Brummell Z, Gorthi G, Pritchard SA, Welch IM.
J Surg Oncol. 2006 Mar 15;93(4):258-67.

Diaphragmatic herniation following esophagogastric resectional surgery: an increasing problem with minimally invasive techniques? : Post-operative diaphragmatic hernias.

Matthews J, Bhanderi S, Mitchell H, Whiting J, Vohra R, Hodson J, Griffiths E.
Surg Endosc. 2016 Apr 22. [Epub ahead of print]

Surgical treatment of a Morgagni hernia causing intermittent gastric outlet obstruction.

Griffiths EA, Ellis A, Mohamed A, Tam E, Ball CS.
BMJ Case Rep. 2010 Nov 5;2010.

Response to Re: Current Australian practice in the diagnosis and management of Barrett’s oesophagus.

Griffiths EA, Farfus AW, Devitt PG, Thompson SK.
ANZ J Surg. 2014 Jul;84(7-8):597

Current Australian practice in the diagnosis and management of Barrett’s oesophagus.

Farfus AW, Griffiths EA, Thompson SK, Devitt PG.
ANZ J Surg. 2013 Dec;83(12):895-8.

Increasing expression of hypoxia-inducible proteins in the Barrett’s metaplasia-dysplasia-adenocarcinoma sequence.

Griffiths EA, Pritchard SA, McGrath SM, Valentine HR, Price PM, Welch IM, West CM.
Br J Cancer. 2007 May 7;96(9):1377-83

FGFR2, HER2 and cMet in gastric adenocarcinoma: detection, prognostic significance and assessment of downstream pathway activation.

Betts G, Valentine H, Pritchard S, Swindell R, Williams V, Morgan S, Griffiths EA, Welch I, West C, Womack C.
Virchows Arch. 2014 Feb;464(2):145-56

Hypoxia-associated markers in gastric carcinogenesis and HIF-2alpha in gastric and gastro-oesophageal cancer prognosis.

Griffiths EA, Pritchard SA, McGrath SM, Valentine HR, Price PM, Welch IM, West CM.
Br J Cancer. 2008 Mar 11;98(5):965-73.

Hypoxia-inducible factor-1alpha expression in the gastric carcinogenesis sequence and its prognostic role in gastric and gastro-oesophageal adenocarcinomas.

Griffiths EA, Pritchard SA, Valentine HR, Whitchelo N, Bishop PW, Ebert MP, Price PM, Welch IM, West CM.
Br J Cancer. 2007 Jan 15;96(1):95-103.

Is the hypoxia-inducible factor pathway important in gastric cancer?

Griffiths EA, Pritchard SA, Welch IM, Price PM, West CM.
Eur J Cancer. 2005 Dec;41(18):2792-805.

Tracheo-oesophageal fistula after palliative treatment of oesophageal cancer.

Hamer PW, Griffiths EA, Devitt PG.
J Gastrointest Oncol. 2015 Oct;6(5):E86-8

Should oesophageal stents be used before neo-adjuvant therapy to treat dysphagia in patients awaiting oesophagectomy? Best evidence topic (BET).

Jones CM, Griffiths EA.
Int J Surg. 2014 Sep 25.

Safety implications of oesophageal stents used for the palliation of dysphagia in patients undergoing neoadjuvant therapy for oesophageal malignancy.

Jones CM, Griffiths EA.
J Gastrointest Oncol. 2014 Aug;5(4):E54-5.

An assessment of radiologically inserted transoral and transgastric gastroduodenal stents to treat malignant gastric outlet obstruction.

Miller BH, Griffiths EA, Pursnani KG, Ward JB, Stockwell RC.
Cardiovasc Intervent Radiol. 2013 Dec;36(6):1591-601

The use of biodegradable (SX-ELLA) oesophageal stents to treat dysphagia due to benign and malignant oesophageal disease.

Griffiths EA, Gregory CJ, Pursnani KG, Ward JB, Stockwell RC.
Surg Endosc. 2012 Aug;26(8):2367-75.

eComment. Re: Gastric ulceration following oesophageal stent migration.

Griffiths EA, Powell SL.
Interact Cardiovasc Thorac Surg. 2012 Aug;15(2):322

A systematic review of transarterial embolization versus emergency surgery in treatment of major nonvariceal upper gastrointestinal bleeding.

Beggs AD, Dilworth MP, Powell SL, Atherton H, Griffiths EA.
Clin Exp Gastroenterol. 2014 Apr 16;7:93-104

Retrospective analysis of surgery and trans-arterial embolization for major non-variceal upper gastrointestinal bleeding.

Griffiths EA, McDonald CR, Bryant RV, Devitt PG, Bright T, Holloway RH, Thompson SK.
ANZ J Surg. 2014 Apr 3

Surgical management of peptic ulcer bleeding by Australian and New Zealand upper gastrointestinal surgeons.

Griffiths EA, Devitt PG, Bright T, Watson DI, Thompson SK.
ANZ J Surg. 2013 Mar;83(3):104-8.

Laparoscopic Stapled Cardioplasty-Room for Improvement.

Hamer PW, Griffiths EA, Devitt PG, Watson DI, Thompson SK.
J Gastrointest Surg. 2016 Feb 2

Does the addition of a fundoplication improve outcomes for patients undergoing laparoscopic Heller’s cardiomyotomy?

Mayo D, Griffiths EA, Khan OA, Szymankiewicz MA, Wakefield CW, Thompson SK.
Int J Surg. 2012;10(6):301-4

Laparoscopic stapled cardioplasty for end-stage achalasia.

Griffiths EA, Devitt PG, Jamieson GG, Myers JC, Thompson SK.
J Gastrointest Surg. 2013 May;17(5):997-1001.

Right thoracoabdominal stab injury penetrating the liver and gallbladder: lessons in penetrating knife wounds to the chest and abdomen.

Griffiths EA, Mohamed A, Ball CS.
BMJ Case Rep. 2010 Sep 22;2010.

Traumatic rupture of a gastrointestinal stromal tumour with intraperitoneal bleeding and haematoma formation.

Mohamed A, Griffiths EA, Witkowski M, Witkowska K, Ball CS.
BMJ Case Rep. 2010 Aug 6;2010

Thirty-four cases of esophageal perforation: the experience of a district general hospital in the UK.

Griffiths EA, Yap N, Poulter J, Hendrickse MT, Khurshid M.
Dis Esophagus. 2009;22(7):616-25

Combined endoscopic and laparoscopic approach for palliative resection of metastatic melanoma of the stomach.

Date RS, Griffiths EA, Pritchard SA, Welch IM.
World J Surg Oncol. 2006 Mar 30;4:20.

WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis.

Di Saverio S, Birindelli A, Kelly MD, Catena F, Weber DG, Sartelli M, Sugrue M, De Moya M, Gomes CA, Bhangu A, Agresta F, Moore EE, Soreide K, Griffiths E, De Castro S, Kashuk J, Kluger Y, Leppaniemi A, Ansaloni L, Andersson M, Coccolini F, Coimbra R, Gurusamy KS, Campanile FC, Biffl W, Chiara O, Moore F, Peitzman AB, Fraga GP, Costa D, Maier RV, Rizoli S, Balogh ZJ, Bendinelli C, Cirocchi R, Tonini V, Piccinini A, Tugnoli G, Jovine E, Persiani R, Biondi A, Scalea T, Stahel P, Ivatury R, Velmahos G, Andersson R.
World J Emerg Surg. 2016 Jul 18;11:34.

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA).

Sartelli M, Weber DG, Ruppé E, Bassetti M, Wright BJ, Ansaloni L, Catena F, Coccolini F, Abu-Zidan FM, Coimbra R, Moore EE, Moore FA, Maier RV, De Waele JJ, Kirkpatrick AW, Griffiths EA, Eckmann C, Brink AJ, Mazuski JE, May AK, Sawyer RG, Mertz D, Montravers P, Kumar A, Roberts JA, Vincent JL, Watkins RR, Lowman W, Spellberg B, Abbott IJ, Adesunkanmi AK, Al-Dahir S, Al-Hasan MN, Agresta F, Althani AA, Ansari S, Ansumana R, Augustin G, Bala M, Balogh ZJ, Baraket O, Bhangu A, Beltrán MA, Bernhard M, Biffl WL, Boermeester MA, Brecher SM, Cherry-Bukowiec JR, Buyne OR, Cainzos MA, Cairns KA, Camacho-Ortiz A, Chandy SJ, Che Jusoh A, Chichom-Mefire A, Colijn C, Corcione F, Cui Y, Curcio D, Delibegovic S, Demetrashvili Z, De Simone B, Dhingra S, Diaz JJ, Di Carlo I, Dillip A, Di Saverio S, Doyle MP, Dorj G, Dogjani A, Dupont H, Eachempati SR, Enani MA, Egiev VN, Elmangory MM, Ferrada P, Fitchett JR, Fraga GP, Guessennd N, Giamarellou H, Ghnnam W, Gkiokas G, Goldberg SR, Gomes CA, Gomi H, Guzmán-Blanco M, Haque M, Hansen S, Hecker A, Heizmann WR, Herzog T, Hodonou AM, Hong SK, Kafka-Ritsch R, Kaplan LJ, Kapoor G, Karamarkovic A, Kees MG, Kenig J, Kiguba R, Kim PK, Kluger Y, Khokha V, Koike K, Kok KY, Kong V, Knox MC, Inaba K, Isik A, Iskandar K, Ivatury RR, Labbate M, Labricciosa FM, Laterre PF, Latifi R, Lee JG, Lee YR, Leone M, Leppaniemi A, Li Y, Liang SY, Loho T, Maegele M, Malama S, Marei HE, Martin-Loeches I, Marwah S, Massele A, McFarlane M, Melo RB, Negoi I, Nicolau DP, Nord CE, Ofori-Asenso R, Omari AH, Ordonez CA, Ouadii M, Pereira Júnior GA, Piazza D, Pupelis G, Rawson TM, Rems M, Rizoli S, Rocha C, Sakakhushev B, Sanchez-Garcia M, Sato N, Segovia Lohse HA, Sganga G, Siribumrungwong B, Shelat VG, Soreide K, Soto R, Talving P, Tilsed JV, Timsit JF, Trueba G, Trung NT, Ulrych J, van Goor H, Vereczkei A, Vohra RS, Wani I, Uhl W, Xiao Y, Yuan KC, Zachariah SK, Zahar JR, Zakrison TL, Corcione A, Melotti RM, Viscoli C, Viale P.
World J Emerg Surg. 2016 Jul 15;11:33.

Duration of Antimicrobial Therapy in Treating Complicated Intra-Abdominal Infections: A Comprehensive Review.

Sartelli M, Catena F, Ansaloni L, Coccolini F, Di Saverio S, Griffiths EA.
Surg Infect (Larchmt). 2016 Jan;17(1):9-12

Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections: a prospective multicentre study (WISS Study).

Sartelli M, Abu-Zidan FM, Catena F, Griffiths EA, Di Saverio S, Coimbra R, Ordoñez CA, Leppaniemi A, Fraga GP, Coccolini F, Agresta F, Abbas A, Abdel Kader S, Agboola J, Amhed A, Ajibade A, Akkucuk S, Alharthi B, Anyfantakis D, Augustin G, Baiocchi G, Bala M, Baraket O, Bayrak S, Bellanova G, Beltràn MA, Bini R, Boal M, Borodach AV, Bouliaris K, Branger F, Brunelli D, Catani M, Che Jusoh A, Chichom-Mefire A, Cocorullo G, Colak E, Costa D, Costa S, Cui Y, Curca GL, Curry T, Das K, Delibegovic S, Demetrashvili Z, Di Carlo I, Drozdova N, El Zalabany T, Enani MA, Faro M, Gachabayov M, Giménez Maurel T, Gkiokas G, Gomes CA, Gonsaga RA, Guercioni G, Guner A, Gupta S, Gutierrez S, Hutan M, Ioannidis O, Isik A, Izawa Y, Jain SA, Jokubauskas M, Karamarkovic A, Kauhanen S, Kaushik R, Kenig J, Khokha V, Kim JI, Kong V, Koshy R, Krasniqi A, Kshirsagar A, Kuliesius Z, Lasithiotakis K, Leão P, Lee JG, Leon M, Lizarazu Pérez A, Lohsiriwat V, López-Tomassetti Fernandez E, Lostoridis E, Mn R, Major P, Marinis A, Marrelli D, Martinez-Perez A, Marwah S, McFarlane M, Melo RB, Mesina C, Michalopoulos N, Moldovanu R, Mouaqit O, Munyika A, Negoi I, Nikolopoulos I, Nita GE, Olaoye I, Omari A, Ossa PR, Ozkan Z, Padmakumar R, Pata F, Pereira Junior GA, Pereira J, Pintar T, Pouggouras K, Prabhu V, Rausei S, Rems M, Rios-Cruz D, Sakakushev B, Sánchez de Molina ML, Seretis C, Shelat V, Simões RL, Sinibaldi G, Skrovina M, Smirnov D, Spyropoulos C, Tepp J, Tezcaner T, Tolonen M, Torba M, Ulrych J, Uzunoglu MY, van Dellen D, van Ramshorst GH, Vasquez G, Venara A, Vereczkei A, Vettoretto N, Vlad N, Yadav SK, Yilmaz TU, Yuan KC, Zachariah SK, Zida M, Zilinskas J, Ansaloni L.
World J Emerg Surg. 2015 Dec 16;10:61.

Emergency surgery in the elderly: challenges and solutions.

Torrance AD, Powell SL, Griffiths EA.
Open Access Emerg Med. 2015 Sep 8;7:55-68.

WSES guidelines for management of Clostridium difficile infection in surgical patients.

Sartelli M, Malangoni MA, Abu-Zidan FM, Griffiths EA, Di Bella S, McFarland LV, Eltringham I, Shelat VG, Velmahos GC, Kelly CP, Khanna S, Abdelsattar ZM, Alrahmani L, Ansaloni L, Augustin G, Bala M, Barbut F, Ben-Ishay O, Bhangu A, Biffl WL, Brecher SM, Camacho-Ortiz A, Caínzos MA, Canterbury LA, Catena F, Chan S, Cherry-Bukowiec JR, Clanton J, Coccolini F, Cocuz ME, Coimbra R, Cook CH, Cui Y, Czepiel J, Das K, Demetrashvili Z, Di Carlo I, Di Saverio S, Dumitru IM, Eckert C, Eckmann C, Eiland EH, Enani MA, Faro M, Ferrada P, Forrester JD, Fraga GP, Frossard JL, Galeiras R, Ghnnam W, Gomes CA, Gorrepati V, Ahmed MH, Herzog T, Humphrey F, Kim JI, Isik A, Ivatury R, Lee YY, Juang P, Furuya-Kanamori L, Karamarkovic A, Kim PK, Kluger Y, Ko WC, LaBarbera FD, Lee JG, Leppaniemi A, Lohsiriwat V, Marwah S, Mazuski JE, Metan G, Moore EE, Moore FA, Nord CE, Ordoñez CA, Júnior GA, Petrosillo N, Portela F, Puri BK, Ray A, Raza M, Rems M, Sakakushev BE, Sganga G, Spigaglia P, Stewart DB, Tattevin P, Timsit JF, To KB, Tranà C, Uhl W, Urbánek L, van Goor H, Vassallo A, Zahar JR, Caproli E, Viale P.
World J Emerg Surg. 2015 Aug 20;10:38

The role of the open abdomen procedure in managing severe abdominal sepsis: WSES position paper.

Sartelli M, Abu-Zidan FM, Ansaloni L, Bala M, Beltrán MA, Biffl WL, Catena F, Chiara O, Coccolini F, Coimbra R, Demetrashvili Z, Demetriades D, Diaz JJ, Di Saverio S, Fraga GP, Ghnnam W, Griffiths EA, Gupta S, Hecker A, Karamarkovic A, Kong VY, Kafka-Ritsch R, Kluger Y, Latifi R, Leppaniemi A, Lee JG, McFarlane M, Marwah S, Moore FA, Ordonez CA, Pereira GA, Plaudis H, Shelat VG, Ulrych J, Zachariah SK, Zielinski MD, Garcia MP, Moore EE.
World J Emerg Surg. 2015 Aug 12;10:35

The challenge of post-operative peritonitis after gastrointestinal surgery.

Sartelli M, Griffiths EA, Nestori M.
Updates Surg. 2015 Aug 12

A proposal for a CT driven classification of left colon acute diverticulitis.

Sartelli M, Moore FA, Ansaloni L, Di Saverio S, Coccolini F, Griffiths EA, Coimbra R, Agresta F, Sakakushev B, Ordoñez CA, Abu-Zidan FM, Karamarkovic A, Augustin G, Costa Navarro D, Ulrych J, Demetrashvili Z, Melo RB, Marwah S, Zachariah SK, Wani I, Shelat VG, Kim JI, McFarlane M, Pintar T, Rems M, Bala M, Ben-Ishay O, Gomes CA, Faro MP, Pereira GA Jr, Catani M, Baiocchi G, Bini R, Anania G, Negoi I, Kecbaja Z, Omari AH, Cui Y, Kenig J, Sato N, Vereczkei A, Skrovina M, Das K, Bellanova G, Di Carlo I, Segovia Lohse HA, Kong V, Kok KY, Massalou D, Smirnov D, Gachabayov M, Gkiokas G, Marinis A, Spyropoulos C, Nikolopoulos I, Bouliaris K, Tepp J, Lohsiriwat V, Çolak E, Isik A, Rios-Cruz D, Soto R, Abbas A, Tranà C, Caproli E, Soldatenkova D, Corcione F, Piazza D, Catena F.
World J Emerg Surg. 2015 Feb 19;10:3.

Primary osteogenic sarcoma of the breast: A case report.

Khan S, Griffiths EA, Shah N, Ravi S.
Cases J. 2008 Sep 10;1(1):148

Surgical excision of an abdominal wall granular cell tumour with Permacol(R) mesh reconstruction: a case report.

Chaudhry A, Griffiths EA, Shah N, Ravi S.
Int Semin Surg Oncol. 2008 Feb 25;5:4

Bifid vermiform appendix: a case report.

Griffiths EA, Jagadeesan J, Fasih T, Mercer-Jones M.
Curr Surg. 2006 May-Jun;63(3):176-8.

Symptomatic breast clinic: an efficient resource.

Kalbassi MR, Griffiths EA, Hemming JD, Cunliffe WJ, Browell DA.
Breast J. 2006 Jan-Feb;12(1):93-4

Evaluation of a pre-operative staging protocol in the management of colorectal carcinoma.

Griffiths EA, Browell DA, Cunliffe WJ.
Colorectal Dis. 2005 Jan;7(1):35-42.

Re: Perforation of the terminal ileum: a possible complication of nicrorandil therapy. Surg J R Coll Surg Edinb Irel. 2004: 56-57.

Griffiths EA.
Surgeon. 2004 Oct;2(5):296;

Acute inflammation of a congenital cecal diverticulum mimicking appendicitis.

Griffiths EA, Bergin FG, Henry JA, Mudawi AM.
Med Sci Monit. 2003 Dec;9(12):CS107-9.

Comparative in vivo lung delivery of hydrofluoroalkane-salbutamol formulation via metered-dose inhaler alone, with plastic spacer, or with cardboard tube.

Fowler SJ, Wilson AM, Griffiths EA, Lipworth BJ.
Chest. 2001 Apr;119(4):1018-20.

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